Evidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinoma

Table 4 Genes selected for quantitative RT-PCR experiments

	Gene symbol	Microarray (fold change)	Quantitative RT-PCR (fold change)
Target genes	CGI-41	5.3	1.9
	C16orf5	5.5	2.6^a
	GOSR2	4.0	2.9^a
	MARK3	4.9	-1.4
	LOX	-2.0	-11.6^a
	STK25	2.0	-1.5
	SULF-1	-4.0	-11.9^a
	TXNL2	4.2	3.0^a

Positive and negative numbers indicate upregulated and downregulated genes in pure DCIS, respectively. ^aGenes confirmed using both methodologies. DCIS, ductal carcinoma in situ.

ISSN: 1465-542X