Skip to main content

Table 2 Top 20 putative hypomethylated gene targets detected by promoter analyses of 468GFP and 468LN cells

From: Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays

Description

Gene symbol

Chromosome

Fold change

Chromogranin A (parathyroid secretory protein 1)

CHGA

14q32

6.44

DKFZP434B0335 protein

DKFZP434B0335

7q21.3

3.73

Zinc finger, C3HC-type containing 1

ZC3HC1

7q32.2

3.41

Centrosomal protein 57 kDa

CEP57

11q21

3.22

Stromal antigen 1

STAG1

3q22.3

3.12

Vesicle-associated membrane protein 3 (cellubrevin)

VAMP3

1q36.23

3.07

Ectonucleoside triphosphate diphosphohydrolase 7

ENTPD7

10q24.2

2.98

Transmembrane emp24 domain trafficking protein 2

TMED2

12q24.31

2.97

Glycoprotein V (platelet)

GP5

3q29

2.96

CATR tumorigenicity conversion 1

CATR1

7q32

2.87

Nuclear receptor subfamily 2, group C, member 2

NR2C2

3p25

2.83

Small EDRK-rich factor 1A (telomeric)

SERF1A

5q12.2-q13.3

2.83

Transcription factor 12

TCF12

15q21

2.82

Zinc finger and BTB domain containing 20

ZBTB20

3q13.2

2.82

Aurora kinase A interacting protein 1

AURKAIP1

1p36.33

2.82

Sorting nexin 1

SNX1

15q22.31

2.82

LOC136263

LOC136263

7q32.2

2.81

NEDD8 ultimate buster-1

NYREN18

7q36

2.77

Testis specific, 13

TSGA13

7q32

2.76

Solute carrier family 3A, member 2

SLC3A2

11q13

2.75

  1. The names and descriptions of the genes are given, as well as the fold change in hypomethylation in MDA-MB-468GFP-LN (468LN) cells relative to MDA-MB-468GFP (468GFP) cells.