Figure 1From: BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1tumour phenotypeMap of the BRCA1 promoter region studied by the MethyLight and MS-HRM assays. The numbering of the promoter is according to that used by Rice et al. [24]. TSS denotes the transcription start site. The positions of the primers flanking the MethyLight and MS-HRM amplicons are indicated as well as the position of the MethyLight probe.Back to article page