Figure 6From: The zinc finger domain of Wilms' tumor 1 suppressor gene (WT1) behaves as a dominant negative, leading to abrogation of WT1 oncogenic potential in breast cancer cellsRetarded cell division in the zinc finger domain lacking lysine–threonine–serine-transfected MCF-7 cells. A typical result of three individual assays for the carboxy-fluorescein diacetate succinimidyl ester (CFSE) labeling profiles of gated transfectants of MCF-7 cells. The transfectants (CON and zinc finger domain lacking the lysine–threonine–serine insert (ZF - KTS)) and the days post G418 selection (day 1, day 4, day 7 and day 10) are indicated.Back to article page