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Table 1 Immunohistochemical analysis of 85 primary breast tumors for pStat3, interleukin-6, estrogen receptor, progesterone receptor, and Her2neu

From: Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer

 

pStat3 0, 1+ (54%)

pStat3 2, 3+ (46%)

P value (Fisher)

Interleukin-6 (2, 3+)

11

32

0.001

Interleukin-6 (0, 1+)

34

5

 

Estrogen receptor-positive

21

25

0.20

Estrogen receptor-negative

24

14

 

Progesterone receptor-positive

16

18

1.0

Progesterone receptor-negative

29

19

 

Her2neu (2, 3+)

5

7

1.0

Her2neu (0, 1+)

30

25

 
  1. The correlations between the relationship of pStat3 and interleukin-6, estrogen receptor, progesterone receptor, and Her2neu were measured using the χ2 test. 0 is no staining, 1+ is weak staining, 2+ is moderate staining and 3+ is strong staining for pStat3, tyrosine-phosphorylated signal transducer and activator of transcription 3 and IL-6.
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Breast Cancer Research

ISSN: 1465-542X

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