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  1. This paper describes the derivation and characterization of a novel, conditionally immortal mammary epithelial cell line named KIM-2. These cells were derived from mid-pregnant mammary glands of a mouse harbou...

    Authors: Katrina E Gordon, Bert Binas, Rachel S Chapman, Kathreena M Kurian, Richard W E Clarkson, A John Clark, E Birgitte Lane and Christine J Watson
    Citation: Breast Cancer Research 2000 2:222
  2. Both the non-receptor tyrosine kinase, c-Src, and members of the epidermal growth factor (EGF) receptor family are overexpressed in high percentages of human breast cancers. Because these molecules are plasma ...

    Authors: Jacqueline S Biscardi, Rumey C Ishizawar, Corinne M Silva and Sarah J Parsons
    Citation: Breast Cancer Research 2000 2:203
  3. The fibroblast growth factors [Fgfs (murine), FGFs (human)] constitute a large family of ligands that signal through a class of cell-surface tyrosine kinase receptors. Fgf signalling has been associated in vitro ...

    Authors: Clive Dickson, Bradley Spencer-Dene, Christian Dillon and Vera Fantl
    Citation: Breast Cancer Research 2000 2:191
  4. We tested the hypothesis that BRCA1 may play a role in the regulation of ovarian tumor cell death as well as the inhibition of ovarian cell proliferation. Introduction of BRCA1 antisense retroviral constructs ...

    Authors: Lois A Annab, Rebecca Hawkins, Greg Solomon, J Carl Barrett and Cynthia A Afshari
    Citation: Breast Cancer Research 2000 2:139
  5. Altered responsiveness to extracellular signals and cell cycle dysregulation are hallmarks of cancer. The cell cycle is governed by cyclin-dependent kinases (cdks) that integrate mitogenic and growth inhibitor...

    Authors: Jeffrey Donovan and Joyce Slingerland
    Citation: Breast Cancer Research 2000 2:116

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