Table 1 Age-adjusted characteristics of women with biopsy confirmed benign breast disease in the Nurses’ Health Studies, by cumulative alcohol use and menopausal status
From: Associations of alcohol consumption with breast tissue composition
Characteristic | Premenopausal | Postmenopausal | ||||||
|---|---|---|---|---|---|---|---|---|
None n = 159 | < 11 g/day  = 290 | 11–< 22 g/day n = 56 | ≥ 22 g/day n = 31 | None n = 70 | < 11 g/day n = 140 | 11–< 22 g/day n = 40 | ≥ 22 g/day n = 13 | |
Mean (SD) | Â | Â | Â | Â | Â | Â | Â | Â |
Epithelium % | 10.2 (7.5) | 9.6 (6.3) | 11.3 (6.7) | 11.1 (5.3) | 8.3 (7.7) | 6.4 (4.2) | 8.7 (7.5) | 4.6 (1.7) |
Stroma % | 75.3 (11.1) | 75.3 (11.0) | 75.3 (11.3) | 73.8 (7.0) | 68.4 (10.7) | 67.9 (13.9) | 66.9 (10.4) | 59.0 (6.8) |
Fat % | 14.5 (10.5) | 14.9 (10.9) | 13.5 (12.3) | 15.2 (9.0) | 23.4 (10.1) | 25.7 (14.6) | 24.5 (8.5) | 36.5 (7.9) |
Fibroglandular %a | 85.5 (10.5) | 85.1(10.9) | 86.5 (12.3) | 84.8 (9.0) | 76.7 (10.1) | 74.3 (14.6) | 75.5 (8.5) | 63.6 (7.9) |
Age at BBD biopsy (years)b | 39.4 (7.2) | 41.7 (7.1) | 42.6 (7.4) | 40.2 (7.3) | 58.6 (6.1) | 56.8 (6.9) | 57.4 (6.2) | 55.4 (5.3) |
Age at menarche (years) | 12.7 (1.4) | 12.5 (1.3) | 12.6 (1.3) | 12.7 (1.3) | 12.6 (1.3) | 12.8 (1.3) | 12.6 (1.3) | 12.8 (7.9) |
Age at menopause (years) | NA | NA | NA | NA | 49.0 (4.7) | 48.3 (5.3) | 48.2 (4.4) | 49.0 (2.9) |
Body Mass Index (kg/m2) | 24.9 (5.2) | 24.0 (4.4) | 23.4 (3.6) | 23.1 (3.3) | 25.9 (4.4) | 25.1 (4.0) | 24.9 (3.7) | 24.3 (1.5) |
Percentages | Â | Â | Â | Â | Â | Â | Â | Â |
Parity/age at first birth | Â | Â | Â | Â | Â | Â | Â | Â |
 Nulliparous | 10 | 12 | 5 | 2 | 3 | 7 | 10 | 0 |
 Parous, age < 25 years | 42 | 43 | 36 | 59 | 47 | 48 | 50 | 60 |
 Parous, age ≥ 25 years | 46 | 44 | 59 | 39 | 49 | 45 | 40 | 40 |
Family history of BBD | 8 | 8 | 19 | 33 | 18 | 19 | 13 | 34 |
Benign breast disease | Â | Â | Â | Â | Â | Â | Â | Â |
 Non-proliferative | 34 | 31 | 22 | 18 | 24 | 29 | 32 | 43 |
 Proliferative without atypia | 59 | 57 | 60 | 54 | 58 | 49 | 52 | 35 |
 Proliferative with atypia | 7 | 12 | 18 | 27 | 19 | 22 | 16 | 22 |
Never smoked | 64 | 57 | 32 | 32 | 76 | 42 | 26 | 0 |
Past smoker | 27 | 24 | 40 | 33 | 15 | 40 | 54 | 47 |
Current smoker | 9 | 19 | 28 | 34 | 9 | 18 | 20 | 53 |
Never used MHT | NA | NA | Â | NA | 29 | 35 | 25 | 51 |
Used MHT in the past | NA | NA | Â | NA | 30 | 15 | 21 | 17 |
Currently using MHT | NA | NA | Â | NA | 33 | 39 | 34 | 26 |