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Table 2 Distribution of demographic characteristics by whether the 3-protein signature is accurate

From: Diagnostic accuracy of a three-protein signature in women with suspicious breast lesions: a multicenter prospective trial

Variables

Number of women (%)

  

In Discordant group (n = 189)

In Concordant group (n = 453)

p-value

Age

Mean ± SD

52.1 ± 11.3

52.2 ± 11.4

0.5861)

Height (cm)

n

158 (83.6%)

391 (86.3%)

0.3791)

Unknown

31 (16.4%)

62 (13.7%)

Mean ± SD

158.7 ± 5.6

158.2 ± 6.0

Weight (kg)

n

158 (83.6%)

391 (86.3%)

0.8671)

Unknown

31 (16.4%)

62 (13.7%)

Mean ± SD

59.1 ± 9.6

59.4 ± 9.5

Anti-hypertensive medication

No

156 (82.5%)

374 (82.6%)

0.9952)

Yes

33 (17.5%)

79 (17.4%)

Dyslipidemia medication

No

164 (86.8%)

396 (87.4%)

0.8242)

Yes

25 (13.2%)

57 (12.6%)

Diabetes medication

No

172 (91.0%)

423 (93.4%)

0.2932)

 

Yes

17 (9.0%)

30 (6.6%)

Synthroid medication

No

177 (93.7%)

423 (93.4%)

0.8982)

Yes

12 (6.4%)

30 (6.6%)

Other medication

No

160 (84.7%)

391 (86.3%)

0.5832)

Yes

29 (15.3%)

62 (13.7%)

Breast density grade in mammograma

n

84 (44.4%)

185 (28.8%)

0.8783)

Unknown

105 (55.6%)

268 (41.7%)

 

Grade 1

(Almost entirely fatty)

3 (3.6%)

4 (2.2%)

 

Grade 2

(Scattered fibroglandular densities)

11 (13.1%)

24 (13.0%)

 

Grade 3

(Heterogeneously dense)

42 (50.0%)

98 (53.0%)

 

Grade 4

(Extremely dense)

28 (33.3%)

59 (31.9%)

 

By site

13 institutions

189 (100%)

453 (100%)

0.3832)

  1. SD; standard deviation
  2. aAmerican College of Radiology (ACR) BI-RADS Breast Density Categories
  3. 1)Wilcoxon rank sum test 2)Chi-square test 3)Fisher exact test