Skip to main content
Fig. 6 | Breast Cancer Research

Fig. 6

From: Racial differences in RAD51 expression are regulated by miRNA-214-5P and its inhibition synergizes with olaparib in triple-negative breast cancer

Fig. 6

miR-214-5P mimic abrogates olaparib-induced RAD51 foci formation. A HCC1806 cells transfected with miR-control or miR-214-5P and treated with or without 25 µM olaparib for 24 h were analyzed for RAD51 foci using immunofluorescence. B More than 75 cells from three independent experiments were analyzed for the percentage of cells that shows > 5 RAD51 foci and represented as a histogram with standard error. C HCC1806 cells transfected with miR-control or miR-214-5P and treated with or without 25 µM olaparib for 24 h was analyzed for pH2AX foci using immunofluorescence. D More than 75 cells from three independent experiments were analyzed for percentage of cells that shows > 7 pH2AX foci and represented as a histogram with standard error. (****p < 0.0001)

Back to article page

Breast Cancer Research

ISSN: 1465-542X

Contact us