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Fig. 3 | Breast Cancer Research

Fig. 3

From: Racial differences in RAD51 expression are regulated by miRNA-214-5P and its inhibition synergizes with olaparib in triple-negative breast cancer

Fig. 3

miR-214-5P regulates the expression of RAD51 in TNBC. A Comparison of RAD51 expression in AA (MDAMB468/HCC1806) and EA (MDAMB231/MDAMB453) TNBC cell lines analyzed by RT-PCR in three independent experiments. B Comparison of miR-142-3P expression in AA (MDAMB468/HCC1806) and EA (MDAMB231/MDAMB453) TNBC cell lines analyzed by RT-PCR in three independent experiments. C Comparison of miR-214-5P expression in AA (MDAMB468/HCC1806) and EA (MDAMB231/MDAMB453) TNBC cell lines analyzed by RT-PCR in three independent experiments. D Western blot analysis of RAD51 in MDAMB468 cells transfected with miR-214-5P at time points indicated. E Western blot analysis of RAD51 in MDAMB468 cells transfected with miR-142-3P at time points indicated. F Western blot analysis of RAD51 in TNBC cells transfected with miR-214-5P. G Histogram representation of cell cycle profile in MDAMB468 cells 48 h after transfected with miR-214-5P in three independent experiments. (***p < 0.001) and (****p < 0.0001)

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Breast Cancer Research

ISSN: 1465-542X

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