Table 3 Hazard ratios (95% CI) for all-cause mortality based on the presence of multimorbidity in women with breast cancer in the SABCHO cohort using Cox proportional hazards models

Obesity

745 (41.6)

0.89 (0.80–0.99)^b

0.92 (0.83–1.03)

0.96 (0.87–1.07)

1.05 (0.94–1.17)

Hypertension

575 (43.3)

0.99 (0.89–1.10)

0.95 (0.84–1.07)

1.04 (0.92–1.18)

1.05 (0.93–1.19)

Diabetes

201 (48.0)

1.12 (0.96–1.30)

1.11 (0.95–1.29)

1.21 (1.03–1.42)^a

1.20 (1.03–1.41)^a

Cerebrovascular disease

104 (53.3)

1.30 (1.06–1.58)^b

1.27 (1.04–1.56)^a

1.47 (1.19–1.80)^c

1.43 (1.17–1.76)^b

Asthma/COPD

69 (47.9)

1.04 (0.82–1.33)

1.09 (0.86–1.39)

1.17 (0.91–1.50)

1.22 (0.95–1.56)

HIV

353 (48.6)

1.32 (1.17–1.49)^c

1.44 (1.26–1.64)^c

1.32 (1.16–1.51)^c

1.21 (1.06–1.38)^b

Tuberculosis

110 (51.2)

1.23 (1.01–1.50)^b

1.28 (1.05–1.56)^a

1.16 (0.95–1.42)

1.16 (0.95–1.42)

Obesity + hypertension

336 (41.7)

0.94 (0.83–1.06)

0.94 (0.83–1.07)

1.04 (0.91–1.80)

1.09 (0.96–1.24)

Obesity + HIV

150 (47.9)

1.20 (1.01–1.42)^b

1.28 (1.07–1.52)^b

1.25 (1.05–1.50)^a

1.24 (1.04–1.48)^a

Hypertension + Diabetes

161 (48.1)

1.10 (0.94–1.31)

1.08 (0.91–1.28)

1.19 (1.00–1.41)

1.18 (1.00–1.41)

HIV + Tuberculosis

62 (53.9)

1.39 (1.08–1.79)^b

1.48 (1.46–1.92)^b

1.23 (0.95–1.60)

1.23 (0.95–1.60)

Multimorbidity (≥ 2 chronic conditions)

667 (45.5)

1.12 (1.01–1.24)^b

1.15 (1.03–1.28)^a

1.19 (1.07–1.32)^c

1.26 (1.13–1.40)^c