Table 3 Utilization of the PDxBr training and validation models with cutoff to stratify patients into high- and low-risk recurrence groups
Events | Censored | Total | |
|---|---|---|---|
Training model | |||
*Risk score ≥ 58 | 140 | 295 | 435 |
*Risk score < 58 | 80 | 1044 | 1124 |
Training performance metric | Performance (95% CI) | ||
Sensitivity | 0.715 | ||
Specificity | 0.772 | ||
PPV | 0.319 | ||
NPV | 0.948 | ||
Confidence interval | 0.787 (0.764, 0.808) | ||
Validation model | |||
Risk score ≥ 58 | 39 | 104 | 143 |
Risk score < 58 | 30 | 343 | 373 |
Performance metric | Performance (95% CI) | ||
Sensitivity | 0.605 | ||
Specificity | 0.768 | ||
PPV | 0.242 | ||
NPV | 0.941 | ||
Confidence interval | 0.755 (0.717, 0.792) | ||