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Table 2 Bivariable associations of lifestyle factors and immune cell signatures

From: Association of body mass index and inflammatory dietary pattern with breast cancer pathologic and genomic immunophenotype in the nurses’ health study

Predictor

IHC cohort (N = 262)

Expression only cohort (N = 620)

Beta coefficient

Standard error

P value

Beta coefficient

Standard error

P value

GeparSixto

    

BMI change since age 18

0.01

0.01

0.29

0.01

0.01

0.05

Cumulative average physical activity (MET h/week)

0.0001

0.002

0.98

0.0003

0.001

0.86

EDIP scorea

0.08

0.05

0.10

0.04

0.03

0.15

CD8 + score

    

BMI change since age 18

0.04

0.09

0.69

0.10

0.06

0.08

Cumulative average physical activity (MET h/week)

0.01

0.02

0.50

0.01

0.02

0.71

EDIP scorea

0.79

0.50

0.12

0.08

0.31

0.79

CD4 + score

    

BMI change since age 18

0.16

0.09

0.07

0.17

0.06

0.003

Cumulative average physical activity (MET h/week)

0.01

0.02

0.51

0.003

0.02

0.85

EDIP scorea

0.47

0.52

0.37

0.06

0.32

0.85

CD20 + score

    

BMI change since age 18

− 0.01

0.07

0.85

0.03

0.04

0.54

Cumulative average physical activity (MET hours/week)

0.01

0.02

0.39

− 0.002

0.01

0.85

EDIP scorea

0.66

0.37

0.08

− 0.03

0.24

0.91

CD163 + score

    

BMI change since age 18

0.12

0.11

0.27

0.13

0.06

0.04

Cumulative average physical activity (MET hours/week)

− 0.001

0.02

0.98

0.01

0.02

0.71

EDIP scorea

0.62

0.61

0.31

0.18

0.35

0.61

  1. Bold indicates significant values for expression only cohort
  2. aCumulative average empirical dietary inflammatory pattern (EDIP) score