Fig. 4

Mutational landscape in ER + /HER2- tumors (n = 606). A Barplots representing the frequencies of most frequent mutated driver genes, according to HRD and BRCA 1/2 mutational status. * Fisher's exact test p value < 0.05. B Landscape of pathogenic or likely pathogenic somatic mutations of genes involved in the homologous recombination pathway, BRCA1/2 excluded. C Pie charts of number of pathogenic or likely pathogenic somatic mutations of genes involved in the homologous recombination pathway according to HRD and BRCA 1/2 mutational status