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Fig. 3 | Breast Cancer Research

Fig. 3

From: Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers

Fig. 3

Gene set enrichment analysis in ER + /HER2- tumors (n = 606). A-C Gene set enrichment analysis (GSEA) barplots for HALLMARK collection. Bars represent the normalized enrichment score (NES), using genes differentially expressed between: (A) patients with BRCA-mutated tumors vs patients with BRCA WT HRD-low tumors, (B) patients with BRCA-mutated tumors vs patients with BRCA WT HRD-high tumors, and (C) patients with BRCA WT HRD-low tumors vs patients with BRCA WT HRD-high tumors. Red bars: patients with BRCA-mutated tumors, green bars: patients with BRCA WT HRD-high tumors, blue bars: patients with BRCA WT HRD-low tumors. Light colors represent non-significant p values and dark colors significant p values (< 0.05)

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Breast Cancer Research

ISSN: 1465-542X

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