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Fig. 1 | Breast Cancer Research

Fig. 1

From: Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers

Fig. 1

Distributions of HRD score and S3 proportion according to BRCA 1/2 mutational status and breast cancer subtypes (standard pathological classification or PAM50 subtypes) considering the whole cohort (n = 928). A-C Violin plots representing the distribution of HRD score (A) and signature 3 proportion (C) according to breast cancer standard pathological classification. B-D Violin plots representing the distribution of HRD score (B) and signature 3 proportion (D) according to breast cancer standard pathological classification and BRCA 1/2 mutational status. *Wilcoxon p-value < 0.05. E–G Violin plots representing the distribution of HRD score (E) and signature 3 proportion (G) according to PAM50 subtypes. *Wilcoxon p-value < 0.05. F–H Violin plots representing the distribution of HRD (F) and signature 3 proportion (H) score according to PAM50 subtypes and BRCA 1/2 mutational status

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