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Fig. 3 | Breast Cancer Research

Fig. 3

From: A genome-wide association study of mammographic texture variation

Fig. 3

Genetic correlation and SNP-set test results of V with MD phenotypes, breast cancer risk, and other breast cancer risk factors. a Genetic correlations between V and other traits; b SNP-set test results of the relationship of V and other traits. Results of Models 0 and 2 for V65L and VSUM are shown. Estimates passed the Bonferroni threshold (P < 0.05/40 = 1.25 × 10−3) are marked with triple asterisk (***); estimates with P < 0.01 are marked with double asterisk (**); and estimates with nominal significance (P < 0.05) are marked with single asterisk (*). Genetic correlations between VSUM (Model 2) and MD phenotypes were not estimated due to the out of bounds heritability of V. SNP single-nucleotide polymorphism, MD mammographic density, DA dense area, NDA non-dense area, PD percent density, ER estrogen receptor, BMI body mass index

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