Fig. 4
From: Matrix Gla protein (MGP), GATA3, and TRPS1: a novel diagnostic panel to determine breast origin
Representative cases showing the combined positive using GATA3, TRPS1, and MGP panel in breast cancer. Case 1 shows an ER/PR+ invasive breast carcinoma with high expression of GATA3, TRPS1, and MGP. Case 2 shows a triple-negative invasive breast carcinoma with high expression of TRPS1, moderate expression of MGP, and negative expression of GATA3. Case 3 shows a HER2-positive (3+) invasive micropapillary carcinoma with high expression of MGP, mild expression of GATA3, and negative expression of TRPS1. Case 4 shows an ER/PR+ invasive breast carcinoma with high expression of GATA3, moderate expression of TRPS1, and negative expression of MGP. Case 5 shows a triple-negative invasive breast carcinoma with high expression of TRPS1, but negative expression of GATA3 and MGP. Case 6 shows a triple-negative invasive breast carcinoma with moderate expression of MGP, but negative expression of GATA3 and TRPS1