Source of data | ||||||
---|---|---|---|---|---|---|
ABCS | BCAC‡ | BOSOM | EMC | HEBON | NCR | |
Number of patients | 2763 | 186,594 | 7105 | 3483 | 16,617 | 160,861 |
Eligibility criteria, number of patients excluded | ||||||
Studies from Asian countries | – | 7146 | – | – | – | – |
Patients of non-European descent | 74 | 51,328 | – | – | – | – |
Patients younger than 18 years old | – | 4 | – | – | – | – |
Year of PBC diagnosis before 1990 | – | 4014 | 3126 | – | 1132 | – |
Year of PBC diagnosis missing | – | 15,435 | – | – | 2 | – |
PBC stage 0 | 123 | 38 | 2 | – | – | – |
PBC stage IV | 149 | 1811 | 104 | – | 115 | 7774 |
Patients did not undergo surgery | 24 | 1247 | 43 | 5 | 293 | 9278 |
Number of eligible patients | 2393 | 105,571 | 3830 | 3478 | 15,075 | 143,809 |
No follow-up or follow-up less than 3 months | 173 | 15,804 | 70 | 88 | 2382* | 3396 |
Familiar breast cancer studies | – | 6739 | – | – | – | – |
Studies with less than 10 CBC events | – | 37,994 | – | – | – | – |
Number of patients included in the analysis (number of patients with CBC) | 2220 (44) | 45,034 (1001) | 3760 (288) | 3390 (221) | 12,693 (918) | 140,413 (5753) |
Total number of patients included in the analysis (number of CBC) | 207,510 (8225 of which 6828 invasive and 1397 in situ) |