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Fig. 5 | Breast Cancer Research

Fig. 5

From: Loss of Brca1 and Trp53 in adult mouse mammary ductal epithelium results in development of hormone receptor-positive or hormone receptor-negative tumors, depending on inactivation of Rb family proteins

Fig. 5

Several examples of pathways enriched in GSEA comparing B1/P/Rbf and B1/P models. A-B) Genes of the matrisome A and integrin B gene set were upregulated in B1/P compared to B1/P/Rbf tumors. C–E) Genes of the cell cycle C, homologous recombination D and nucleotide excision repair E were upregulated in B1/P/Rbf compared to B1/P tumors

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Breast Cancer Research

ISSN: 1465-542X

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