Elevated NRAS expression during DCIS is a potential driver for progression to basal-like properties and local invasiveness

Table 1 Up-regulation of NRAS expression levels correlates with features found commonly in basal-like tumors

	NRAS versus ER¹, n = 21		NRAS versus PR, n = 21		NRAS versus HER2, n = 16		NRAS versus Ki67, n = 20		NRAS versus p53, n = 17
	DCIS	IDC	DCIS	IDC	DCIS	IDC	DCIS	IDC	DCIS	IDC
Pearson Correlation:	–0.49	–0.52	–0.31	0.09	0.24	0.3	0.55	0.68	0.54	0.55
P (two-tailed):	0.0341	0.0148	0.2133	0.7012	0.3991	0.2563	0.0187	0.0009	0.0364	0.0233

¹ER, HER2, Ki67, and p53 levels were measured by IHC. NRAS levels were assessed by FISH. See Additional file 1: Table S1 for the levels of biomarkers

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