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Table 1 Clinical information on the DCIS specimens

From: MiRNA expression deregulation correlates with the Oncotype DX® DCIS score

Oncotype DX

DCIS risk score

Group

Low

Intermediate

High

Patient

ID

DX

Score

Age

NG

FU

Years

Treatment

Recurrence

ID

DX

Score

Age

NG

FU

Years

Treatment

Recurrence

ID

DX

Score

Age

NG

FU

Years

Treatment

Recurrence

 

DCIS-L1

11

76

N1

10 ys

RT and AI

NED

DCIS-I1

42

78

N2

7 ys

N/A

NED

DCIS-H1

56

45

N2

7.5 yr

RT

NED

 

DCIS-L2

0

72

N1

1 ys

N/A

NED

DCIS-I2

47

69

N3

8 ys

RT and TAM

NED

DCIS-H2

78

52

N2

8 yr

RT and TAM

NED

 

DCIS-L3

27

74

N2

5.2 ys

RT and AI

Cntl. DCIS (2y)

DCIS-I3

52

66

N2

8 ys

RT and AI

NED

DCIS-H3

64

55

N3

6 yr

RT and A

NED

 

DCIS-L4

0

62

N3

5 ys

no RT, TAM

NED

DCIS-I4

48

59

N3

8 ys

RT and AI

NED

DCIS-H4

73

72

N3

3 yr

RT and A

NED

 

DCIS-L5

8

<=30

N2

4.4 ys

None

NED

DCIS-I5

39

67

N3

N/A

N/A

N/A

DCIS-H5

55

58

N3

6 yr

RT

NED

 

DCIS-L6

27

65

N3

4 ys

RT and TAM

NED

DCIS-I6

40

64

N2

N/A

RT and TAM

N/A

 

DCIS-L7

33

75

N2

2 ys

None

Ipsi. DCIS (2y)

DCIS-I757

39

34

N3

MX

MX

MX

 

DCIS-L8

28

62

N2

8 ys

RT and AI

NED

DCIS-I8

47

57

N2

MX

MX

MX

 

DCIS-L9

23

68

N1

8 ys

TAM, no RT

NED

DCIS-I9

40

76

N3

2 ys

RT

Ipsi. IBC (2y)

 

DCIS-L10

12

66

N2

N/A

N/A

N/A

DCIS-I10

52

67

N3

4 ys

AI

NED

 

DCIS-L11

5

70

N1

N/A

N/A

N/A

 

DCIS-L12

1

72

N2

8 ys

No RT

NED

 

DCIS-L13

5

76

N2

4 ys

No RT

NED

 

DCIS-L14

13

68

N3

7 ys

AI, no RT

NED

 

DCIS-L15

20

66

N2

6 ys

AI, no RT

NED

 

DCIS-L16

22

42

N2

N/A

N/A

N/A

 

DCIS-L17

37

61

N2

6 ys

RT and AI

NED

 

DCIS-L18

15

40

N2

5 ys

N/A

NED

 

DCIS-L19

15

65

N2

4.5 ys

AI, no RT

NED

 

DCIS-L20

0

72

4 ys

AI, no RT

NED

 

DCIS-L21

0

62

N1

N/A

N/A

N/A

 

DCIS-L22

24

>=80

N3

4.5 ys

RT and TAM

NED

 

DCIS-L23

36

79

N3

4 ys

None

NED

 

DCIS-L24

0

44

N1

10 ys

TAM, no RT

NED

 

DCIS-L25

6

73

N2

N/A

N/A

N/A

 

DCIS-L26

28

64

N2

5 ys

AI, no RT

NED

  1. Forty-one DCIS specimens were selected for this study and were separated in three groups including low (n = 26), intermediate (n = 10), and high (n = 5) Oncotype DX® DCIS risk scores. Patient identification (ID), age, Oncotype DX® DCIS score and nuclear grade of the DCIS lesions, treatment and recurrence data are provided in the table
  2. DX Score Oncotype DX ® DCIS score
  3. N Nuclear grade (N1—low, N2—intermediate, N3—high)
  4. FU Years Follow-up (FU) in years (ys), mastectomy (MX)
  5. Treatment No Therapy (none), Mastectomy (MX), Radiotherapy (RT), Aromatase Inhibitors (AI), Tamoxifen (TAM)
  6. Recurrence No evidence of disease (NED), ipsilateral DCIS (Ipsi. DCIS), ipsilateral invasive breast cancer (Ipsi. IBC), contralateral DCIS (Cntl. DCIS)