Characteristic | Tertile of Σ8 PAH exposure during pregnancy | p valuea | Tobacco smoker in the household during pregnancy | p valuea | |||
---|---|---|---|---|---|---|---|
Low, < 1.75 ng/m3 | Medium, 1.75 to < 2.95 ng/m3 | High, ≥ 2.95 ng/m3 | No | Yes | |||
Daughters (n = 182) | |||||||
Age at OS, years, mean (SD) | 15.4 (2.5) | 16.3 (2.4) | 16.8 (2.1) | 0.004 | 16.0 (2.3) | 16.4 (2.5) | 0.32 |
Tanner stage at OS, n (%) | Â | Â | Â | 0.05 | Â | Â | 0.58 |
 Stage 1 or 2 | 19 (30.7) | 5 (8.3) | 10 (16.7) |  | 26 (21.5) | 8 (13.1) |  |
 Stage 3 | 18 (29.0) | 19 (31.7) | 18 (30.0) |  | 36 (29.8) | 19 (31.2) |  |
 Stage 4 or 5 | 22 (35.5) | 35 (58.3) | 30 (50.0) |  | 55 (45.5) | 32 (52.5) |  |
 Unknown | 3 (4.8) | 1 (1.7) | 2 (3.3) |  | 4 (3.3) | 2 (3.3) |  |
Birthweight, grams, mean (SD) | 3286 (431) | 3380 (458) | 3304 (531) | 0.51 | 3376 (455) | 3219 (494) | 0.04 |
BMI at age 9, kg/m2, mean (SD) | 19.6 (4.4) | 20.6 (5.2) | 19.8 (4.4) | 0.54 | 19.8 (4.9) | 20.3 (4.2) | 0.50 |
BMI at OS, kg/m2, mean (SD) | 24.5 (6.5) | 26.7 (7.2) | 26.0 (7.6) | 0.22 | 25.5 (7.1) | 26.2 (7.2) | 0.52 |
Body fat at OS, %, mean (SD) | 29.4 (7.4) | 30.7 (8.3) | 29.8 (8.3) | 0.67 | 29.8 (8.0) | 30.3 (7.8) | 0.65 |
Age at menarche, years, mean (SD) | 11.3 (1.4) | 11.7 (1.3) | 11.7 (1.6) | 0.15 | 11.6 (1.5) | 11.5 (1.4) | 0.66 |
Smoker in household during pregnancy, n (%) | Â | Â | Â | 0.84 | Â | Â | Â |
 Yes | 19 (30.7) | 21 (35.0) | 21 (35.0) |  |  |  |  |
 No | 43 (69.4) | 39 (65.0) | 39 (65.0) |  |  |  |  |
Pyrene exposure during pregnancy, ng/m3, mean (SD) | 2.9 (2.1) | 2.9 (1.3) | 3.9 (2.3) | 0.007 | 3.2 (2.1) | 3.2 (1.7) | 0.81 |
Mothers (n = 175) | |||||||
Age at OS, years, mean (SD) | 41.1 (5.8) | 42.4 (5.2) | 42.9 (5.3) | 0.20 | 42.6 (5.2) | 41.1 (5.8) | 0.08 |
Race and ethnicity, n (%) | Â | Â | Â | 0.66 | Â | Â | 0.001 |
 Non-Hispanic Black | 20 (33.9) | 22 (38.6) | 18 (30.5) |  | 30 (25.6) | 30 (51.7) |  |
 Hispanic | 39 (66.1) | 35 (61.4) | 41 (69.5) |  | 87 (74.4) | 28 (48.3) |  |
Education during pregnancy, n (%) | Â | Â | Â | 0.70 | Â | Â | 0.95 |
 High school degree or less | 44 (74.6) | 43 (76.8) | 47 (81.0) |  | 90 (77.6) | 44 (77.2) |  |
 More than high school | 15 (25.4) | 13 (23.2) | 11 (19.0) |  | 26 (22.4) | 13 (22.8) |  |
Public assistance during pregnancy, n (%) | Â | Â | Â | 0.98 | Â | Â | 0.28 |
 Yes | 30 (50.9) | 29 (50.9) | 28 (49.1) |  | 55 (47.4) | 32 (56.1) |  |
 No | 29 (49.2) | 28 (49.1) | 29 (50.9) |  | 61 (52.6) | 25 (43.9) |  |
Pre-pregnancy BMI, kg/m2, mean (SD) | 24.6 (4.5) | 26.9 (7.5) | 25.9 (4.9) | 0.12 | 25.5 (5.4) | 26.4 (6.6) | 0.36 |
Weight gain during pregnancy, kg, mean (SD) | 13.4 (7.9) | 12.0 (6.3) | 11.9 (6.5) | 0.42 | 11.9 (6.6) | 13.5 (7.3) | 0.14 |
BMI at OS, kg/m2, mean (SD) | 29.9 (6.5) | 31.7 (7.7) | 30.7 (6.9) | 0.41 | 30.3 (6.9) | 31.6 (7.2) | 0.24 |
Body fat at OS, %, mean (SD) | 36.2 (7.6) | 37.2 (6.0) | 36.7 (7.0) | 0.77 | 36.2 (6.7) | 37.6 (7.2) | 0.24 |
Tobacco smoker in the household during pregnancy, n (%) | Â | Â | Â | 0.86 | Â | Â | Â |
 Yes | 18 (30.5) | 20 (35.1) | 20 (33.9) |  |  |  |  |
 No | 41 (69.5) | 37 (64.9) | 39 (66.1) |  |  |  |  |
Pyrene exposure during pregnancy, ng/m3, mean (SD) | 2.9 (2.2) | 2.8 (1.2) | 3.9 (2.3) | 0.006 | 3.3 (2.1) | 3.1 (1.7) | 0.61 |