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Fig. 2 | Breast Cancer Research

Fig. 2

From: High AUF1 level in stromal fibroblasts promotes carcinogenesis and chemoresistance and predicts unfavorable prognosis among locally advanced breast cancer patients

Fig. 2

Neoadjuvant therapy-dependent downregulation of AUF1 in tumors improves patient survival. Tissue sections cut from paired FFPE obtained pre-treatment and post-treatment were immunostained with an anti-AUF1 antibody. A Selected photographs obtained by the light microscope Olympus BX53 (Envision 40x). Scale bar = 50 μm. B Graphs depicting the effect of neoadjuvant therapy on the expression level of AUF1. (****P < 0.0001). C Kaplan–Meier analysis of overall survival (OS) and disease-free survival (DFS). Purple: AUF1 level down to < 10%, blue: AUF1 level not affected, green: AUF1 level up to ≥ 10%, brown: AUF1 level up/down but did not reach 10%

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Breast Cancer Research

ISSN: 1465-542X

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