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Table 1 Comparison of clinicopathological features of TNBC patients bearing positive or negative CAIX tumour cell expression

From: Hypoxia-regulated carbonic anhydrase IX (CAIX) protein is an independent prognostic indicator in triple negative breast cancer

Factors CAIX
CAIX negative CAIX positive P value
Age at diagnosisa (years) 55.5 (47, 63) 55 (44, 61.8) 0.230
Ethnicity    0.617
 Chinese 153 (84.1%) 93 (78.8%)  
 Indian 9 (4.9%) 8 (6.8%)  
 Malay 9 (4.9%) 6 (5.1%)  
 Others 11 (6%) 11 (9.3%)  
Laterality    0.642
 Left 98 (52.4%) 60 (49.2%)  
 Right 89 (47.6%) 62 (50.8%)  
Histological grade    < 0.001*
 1/2 40 (21.7%) 8 (6.6%)  
 3 144 (78.3%) 114 (93.4%)  
Tumour size 20 mm    0.002*
 ≤ 20 mm 70 (38.7%) 25 (21.4%)  
 > 20 mm 111 (61.3%) 92 (78.6%)  
Lymphovascular invasion    0.058
 No 122 (68.9%) 64 (57.7%)  
 Yes 55 (31.1%) 47 (42.3%)  
Lymph node positivity    0.072
 Absent 84 (62.7%) 44 (50.0%)  
 Present 50 (37.3%) 44 (50.0%)  
Tumour borders    0.112
 Infiltrative 131 (97.0%) 78 (91.8%)  
 Pushing 4 (3.0%) 7 (8.2%)  
  1. *Statistically significant values (P < 0.05)
  2. aAge is presented as median (Interquartile range)