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Table 1 Comparison of clinicopathological features of TNBC patients bearing positive or negative CAIX tumour cell expression

From: Hypoxia-regulated carbonic anhydrase IX (CAIX) protein is an independent prognostic indicator in triple negative breast cancer

Factors

CAIX

CAIX negative

CAIX positive

P value

Age at diagnosisa (years)

55.5 (47, 63)

55 (44, 61.8)

0.230

Ethnicity

  

0.617

 Chinese

153 (84.1%)

93 (78.8%)

 

 Indian

9 (4.9%)

8 (6.8%)

 

 Malay

9 (4.9%)

6 (5.1%)

 

 Others

11 (6%)

11 (9.3%)

 

Laterality

  

0.642

 Left

98 (52.4%)

60 (49.2%)

 

 Right

89 (47.6%)

62 (50.8%)

 

Histological grade

  

< 0.001*

 1/2

40 (21.7%)

8 (6.6%)

 

 3

144 (78.3%)

114 (93.4%)

 

Tumour size 20 mm

  

0.002*

 ≤ 20 mm

70 (38.7%)

25 (21.4%)

 

 > 20 mm

111 (61.3%)

92 (78.6%)

 

Lymphovascular invasion

  

0.058

 No

122 (68.9%)

64 (57.7%)

 

 Yes

55 (31.1%)

47 (42.3%)

 

Lymph node positivity

  

0.072

 Absent

84 (62.7%)

44 (50.0%)

 

 Present

50 (37.3%)

44 (50.0%)

 

Tumour borders

  

0.112

 Infiltrative

131 (97.0%)

78 (91.8%)

 

 Pushing

4 (3.0%)

7 (8.2%)

 
  1. *Statistically significant values (P < 0.05)
  2. aAge is presented as median (Interquartile range)