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Fig. 3 | Breast Cancer Research

Fig. 3

From: CCR5 activation and endocytosis in circulating tumor-derived cells isolated from the blood of breast cancer patients provide information about clinical outcome

Fig. 3

CCR5 Signal Patterns within the Circulating Cells of Breast Cancer Patients. Four examples of CCR5 expressions in CAMLs are shown with the cytoplasm (green), the nucleus (light blue) and CCR5 pools (red). a Example of a cell with most of the CCR5 pools on the periphery of the cell. Enlarged view shows CCR5 pools around the perimeter of cell b Example of a cell with high CCR5 pooling that appears translocated to in and around the nucleus. c Example of a cell with very few internal CCR5 pools. Enlarged view shows the few clear CCR5 pools. d Example of a cell with mostly “diffuse” CCR5 signal which overlaps throughout the cytoplasmic area, including the nucleus, with a small number of CCR5 pools (white arrow). Scale bar is 20 µm

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