Fig. 6

Effect of PD-L1 and MT Oas2 on primary tumor initiation and expansion in parous mice. Kaplan–Meier survival analysis for the indicated periods and endpoints, and for the indicated genotypes, MT, mutant Oas2; WT wild type Oas2 and treatments (PD-L1 or IgG IP twice weekly), of mouse cohorts (20 per group). All mammary glands were palpated twice weekly and tumor growth was measured by calipers. Individual tumor growth profiles are shown in as shown in Additional file 7: Fig. S5. Two-way Kaplan–Meier comparisons and p values are shown in Additional file 8: Fig. S6, n = 8 WT PD-L1, 8 WT IgG, 14 MT PD-L1, 15 MT IgG