Fig. 3

Effect of MT Oas2 and parity on primary tumor initiation and expansion. Kaplan–Meier survival analysis for the indicated periods and endpoints, and for the indicated genotypes (MT, mutant Oas2; WT wild type Oas2) and parity status of mouse cohorts (20 per group). Mammary glands were palpated twice weekly and tumor growth was measured, as detailed in Additional file 3: Fig. S1. Two-way Kaplan–Meier curve comparisons and p values shown in Additional file 4: Fig. S2, n = 19 MT parous, 21 WT parous, 20 MT nulliparous and 19 WT nulliparous.