Fig. 1

Manhattan plots of the GWAS meta-analysis results of mammographic a dense area (DA, N = 24,579), b non-dense area (NDA, N = 24,689), and c percent mammographic density (PMD, N = 27,900). p value thresholds for genome-wide significance (p = 5 × 10⁻⁸, red dash line) and suggestive significance (p = 10⁻⁵, blue dash line) are shown as horizontal lines. The gene closest to each lead variant is annotated. Novel loci are marked red. a Manhattan plot of the GWAS meta-analysis results of DA. b Manhattan plot of the GWAS meta-analysis results of NDA. c Manhattan plot of the GWAS meta-analysis results of PMD