Fig. 2
From: PTHrP induces STAT5 activation, secretory differentiation and accelerates mammary tumor development
PTHrP overexpression induces the expression of milk proteins and markers of secretory differentiation. A Immunohistochemical staining of mammary gland sections of 8–12-week-old mice. Representative images from each group are shown. N = 3, Scale bar 100 µm. B QPCR analysis for the expression of milk protein and transcription factor genes from whole mammary glands of 8–12-week-old mice. Hprt1 was used as housekeeping gene. C Western blot analysis of protein lysates from mammary glands of 8–12-week-old mice. Samples from three different mice per group were run with β-Actin as the loading control. Bars represent mean ± SEM, n = 3 per group, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05