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Table 2 Risk of breast cancer in men in relation to infertility

From: Infertility and risk of breast cancer in men: a national case–control study in England and Wales

Infertility Cases
No. %
Controls
No. %
Odds ratioa (95% CI)
All subjects
P Odds ratioa (95% CI) excluding men with potentially confounding conditionsb P
No 1810 90.6 1503 94.1 1.00   1.00  
Yes 112 5.6 80 5.0 1.29 (0.94–1.77) 0.11 1.11 (0.78–1.58) 0.55
 Source: self 50 2.5 22 1.4 2.03 (1.18–3.49) 0.01 1.59 (0.82–3.10) 0.17
 Source: partner 31 1.6 34 2.1 0.86 (0.51–1.45) 0.58 0.92 (0.54–1.56) 0.75
 Source: not known or other 31 1.6 24 1.5 1.26 (0.71, 2.24) 0.44 1.05 (0.56–1.98) 0.87
Not known if infertile 76 3.8 14 0.9 1.53 (0.80–2.93) 0.20 1.40 (0.73–2.70) 0.31
Total 1998 100.0 1597 100.0     
  1. CI, confidence interval
  2. aAdjusted for age, socio-economic status (Acorn score [20]), year of interview, marital status and geographical region of residence
  3. bExcluding 11 men with Klinefelter syndrome, 9 with potentially confounding prior cancers, 29 who were severely obese at age 20 (2) or at age 40 (27), and 169 with testicular diseases