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Fig. 4 | Breast Cancer Research

Fig. 4

From: Radiomics predicts the prognosis of patients with locally advanced breast cancer by reflecting the heterogeneity of tumor cells and the tumor microenvironment

Fig. 4

The association between radiomics score and gene expression pattern. a, b GSEA analysis in low-score group and high-score group. Hallmark gene sets with p value < 0.05 were presented. Estrogen response pathway, DNA repair pathway, mTOR pathway, and interferon pathway were enriched. c Volcano plot showed upregulated and downregulated genes in low-score group and high-score group. Over 170 DEGs were identified. d–g function annotation was performed in DEGs. GO analysis showed that DEGs were relate to cornification, keratinization, and keratinocyte differentiation, suggesting that low-score group were different from high-score group in terms of cell differentiation

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Breast Cancer Research

ISSN: 1465-542X

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