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Fig. 3 | Breast Cancer Research

Fig. 3

From: Breast cancer metastasis to brain results in recruitment and activation of microglia through annexin-A1/formyl peptide receptor signaling

Fig. 3

ANXA1 in 4T1 metastatic mammary cancer cells secretome promotes BV-2 microglial directional migration. a–d BV-2 microglial cells were treated with indicated concentrations of a SFM, 4T1 CM or 4T1 ΔANXA1 CM, b recombinant ANXA1 protein, c 4T1 CM supplemented with Boc-MLF FPR1 antagonist or d WRW4 FPR2 antagonist for 24 h in transwell migration assay. Data represent mean ± SEM; n = 3 independent experiments. Images are representative of three independent experiments. ****P < 0.0001

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Breast Cancer Research

ISSN: 1465-542X

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