Table 2 Summary of the significant parameters for different malignant grades and molecular subtypes

Histologic type

 Benign (310)

Fibroadenoma (109)

49.5 ± 33.8

143.0 ± 64.5

448.6 ± 262.8

5.9 ± 9.8

0.92 ± 0.43

2.8 ± 6.2

 Benign changes (77)

44.5 ± 38.6

146.4 ± 94.0

356.9 ± 291.6

2.9 ± 5.4

0.83 ± 0.38

1.2 ± 2.6

 Fibrocystic changes (30)

48.6 ± 31.9

171.1 ± 104.4

429.3 ± 282.6

4.4 ± 7.9

0.87 ± 0.43

1.7 ± 4.0

 Papilloma (28)

51.8 ± 39.2

186.7 ± 88.3

454.0 ± 273.3

3.4 ± 4.2

0.95 ± 0.28

1.3 ± 1.8

 PASH (22)

36.3 ± 28.3

139.8 ± 79.6

438.7 ± 247.5

3.1 ± 3.8

0.95 ± 0.27

1.0 ± 1.6

 Fat necrosis (18)

97.1 ± 70.6

203.5 ± 184.1

574.9 ± 106.2

3.9 ± 3.0

1.1 ± 0.11

1.5 ± 1.3

 Atypical (14)

51.2 ± 34.3

192.3 ± 105.3

303.4 ± 305.7

5.1 ± 9.9

0.75 ± 0.48

2.7 ± 5.6

 Duct ectasia (6)

45.9 ± 20.7

231.8 ± 86.7

501.0 ± 270.8

2.5 ± 2.1

0.95 ± 0.19

0.5 ± 0.5

 Adenoma (4)

47.9 ± 29.1

99.2 ± 56.2

655.4 ± 165.2

22 ± 22.7

1.28 ± 0.23

10.5 ± 13.0

 Others (2)

103.0 ± 95.8

243.9 ± 71.1

708.5 ± 238.7

10 ± 11.3

1.24 ± 0.25

7 ± 8.5

 p value^a

.03

.02

.03

.003

.01

.06

Malignant (204)

 IDC (136)

161.6 ± 65.1

212.3 ± 124.9

640.9 ± 197.3

15.2 ± 15.9

1.19 ± 0.21

7.4 ± 9.2

 IMC with mixed ductal and lobular features (27)

174.7 ± 68.3

227.8 ± 139.1

593.0 ± 278.2

17.0 ± 18.4

1.16 ± 0.23

8.2 ± 10.1

 ILC (24)

168.8 ± 56.2

241.1 ± 128.9

567.6 ± 268.8

14.6 ± 25.0

1.14 ± 0.19

7.3 ± 14.6

 DCIS (15)

94.6 ± 74.5

253.3 ± 172.6

503.8 ± 291.7

7.3 ± 5.9

1.11 ± 0.23

3.7 ± 3.4

 Other (2)

154.1 ± 48.5

97.2 ± 90.6

811.4 ± 142.3

100 ± 76.4

1.50 ± 0.13

69 ± 46.7

 p value^a

.55

.48

.22

.33

.21

.31

Histologic grade

 I (54)

139.1 ± 69.2

278.5 ± 117.1

553.6 ± 244.3

7.5 ± 8.3

1.10 ± 0.20

3.5 ± 4.4

 II (92)

168.0 ± 66.0

220.6 ± 140.7

617.7 ± 210.2

15.0 ± 16.3

1.18 ± 0.18

7.3 ± 9.2

 III (54)

165.8 ± 64.2

155.6 ± 90.8

673.9 ± 233.5

24.1 ± 28.6

1.24 ± 0.24

12.4 ± 18.3

 p value^a

.05

 < .001

.02

 < .001

 < .001

 < .001

Molecular subtypes

 Luminal A (76)

155.7 ± 66.4

257.3 ± 120.5

577.0 ± 241.4

10.8 ± 14.2

1.13 ± 0.21

5.2 ± 8.0

 Luminal B (HER2-) (58)

176.4 ± 61.4

218.2 ± 139.0

625.5 ± 181.0

15.2 ± 15.7

1.18 ± 0.16

7.4 ± 9.3

 Luminal B (HER2 +) (21)

198.4 ± 49.8

136.2 ± 98.4

727.1 ± 155.5

28.6 ± 32.6

1.30 ± 0.13

14.5 ± 21.8

 HER2 + (4)

169.1 ± 31.5

95.5 ± 33.2

628.7 ± 149.6

15.8 ± 14.5

1.20 ± 0.18

7.3 ± 6.4

 TNBC (20)

131.6 ± 65.4

189.3 ± 85.6

543.2 ± 311.5

13.9 ± 16.3

1.11 ± 0.35

7.3 ± 10.8

 p value^a

.005

 < .001

.07

.002

.01

.02