Table 3 Breast cancer HER2 staining percentage by germline PV status
Case no. (N) | HER2− | HER2 + | p value | |
|---|---|---|---|---|
BRCA1 | 56 | 55 (98.2%) | 1 (1.8%) | 0.000 |
BRCA2 | 60 | 57 (95.0%) | 3 (5.0%) | 0.001 |
PALB2 | 22 | 20 (90.9%) | 2 (9.1%) | 0.186 |
ATM | 22 | 17 (77.3%) | 5 (22.7%) | 1.000 |
TP53 | 21 | 13 (61.9%) | 8 (38.1%) | 0.113 |
CHEK2 | 39 | 31 (79.5%) | 8 (20.5%) | 1.000 |
MMRs | 18 | 11 (61.1%) | 7 (38.9%) | 0.146 |
PTEN | 6 | 6 (100%) | 0 (0.0%) | 0.346 |
CDH1 | 3 | 3 (100%) | 0 (0.0%) | 1.000 |
Control/Reference | 355 | 276 (77.7%) | 79 (22.3%) | – |