Fig. 3
From: Gene expression predicts dormant metastatic breast cancer cell phenotype
scRNA-seq analysis of dormant vs proliferative PyMT-Bo1 cells from bone. a Distribution of sequencing read coverage across single dormant (DiD +) vs proliferative (DiD-) PyMT-Bo1 cells. b Transcript profile of DiD- and DiD + single cells showing expression levels of luc2 and mApple. c Heatmap of 3673 differentially expressed genes in dormant (DiD +) versus proliferative (DiD-) cells. d Gene set enrichment analysis revealing biological processes enriched in dormant (DiD +) and proliferative (DiD-) PyMT-Bo1 cells, respectively. e Transcript profile (transcripts per million, TPM) on the Y axis of selected up-regulated genes in dormant DiD + and proliferative DiD- PyMT-Bo1 cells. f Transcript profile (transcripts per million, TPM) on the Y axis of top down-regulated genes in dormant DiD + and proliferative DiD- PyMT-Bo1 cells. g Transcript profile (transcripts per million, TPM) of selected cell cycle related genes in dormant DiD + and proliferative DiD- PyMT-Bo1 cells