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Table 4 The differences in the scores of particular immune cells and growth factor TGF-beta in the group of 30 patients with primary DCIS and in 11 patients with primary DCIS without local recurrence

From: The role of stromal immune microenvironment in the progression of ductal carcinoma in situ (DCIS) to invasive breast cancer

Type of immune cell

Initial scores of immune cells in 30 patients with initial DCIS before recurrence median (range)

Scores of immune cells in 11 patients without recurrence median (range)

p-value

CD20+

5% (1–30)

5% (1–15)

0.942

CD 163+

1% (0–10)

1% (0–3)

0.942

CD 138+

2% (0–30)

< 1% (0–2)*

 < 0.001

CD4+

1% (0–4)

0% (0–2)

0.287

CD8+

2% (1–10)

1% (1–10)

0.717

FOXP3+

0% (0–3)

0% (0–1)

0.513

TGF-Beta (percentage of patients with positive reaction)

30%

18%

0.371

  1. Bold indicates statistical significance level alpha = 0.1
  2. *55% cases no stain, 45% cases 1–2% of stromal area