Table 3 The differences in the scores of particular immune cells and growth factor TGF-beta in the group of 30 patients with primary DCIS and in the same 30 patients with ipsilateral breast recurrence
Type of immune cell | Initial scores of immune cells in 30 patients with initial DCIS before recurrence median (range) | Scores of immune cells in 30 patients after detection of invasive recurrence median (range) | p-value |
|---|---|---|---|
CD20+ | 5% (1–30) | 17.5% (5–60) | < 0.001 |
CD 163+ | 1% (0–10) | 5% (0–20) | < 0.001 |
CD 138+ | 2% (0–30) | 5% (0–20) | 0.100 |
CD4+ | 1% (0–4) | 1% (0–4) | 0.483 |
CD8+ | 2% (1–10) | 2% (0–5) | 0.593 |
FOXP3+ | 0% (0–3) | 1% (0–3) | 0.439 |
TGF-Beta (percentage of patients with the positive reaction) | 30% | 80% | 0.426 |