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Fig. 3 | Breast Cancer Research

Fig. 3

From: Quantitative multiparametric MRI predicts response to neoadjuvant therapy in the community setting

Fig. 3

Representative Ktrans (top) and ADC (bottom) maps over the course of therapy for a woman who had stable disease (patient #4 in Table 1). Median Ktrans values increase over the course of therapy, from 0.10 min−1 at MRI 1 to 0.15 min−1 at MRI 2 and to 0.14 min−1 at MRIs 3 and 4. Mean tumor ADC values are largely unchanged over the course of therapy, from 0.0009 mm2/s at MRIs 1, 2, and 3 to 0.0008 mm2/s at MRI 4. For display purposes, Ktrans and ADC parametric maps are interpolated to the resolution of anatomical images and overlaid on top of the anatomical images. (Note that all analysis was performed on the resolution at which the data were acquired.)

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