Fig. 2
From: Quantitative multiparametric MRI predicts response to neoadjuvant therapy in the community setting
Representative Ktrans (top) and ADC (bottom) maps over the course of therapy for a woman who achieved pCR (patient #9 in Table 1). Median tumor Ktrans values decline over the course of therapy, from 0.12 min−1 at MRI 1 to 0.10 min−1 at MRI 2 to 0.02 min−1 at MRIs 3 and 4. Mean tumor ADC values increase over the course of therapy, from 0.0011 mm2/s at MRIs 1 and 2 to 0.0013 mm2/s at MRIs 3 and 4. For display purposes, Ktrans and ADC parametric maps are interpolated to the resolution of anatomical images and overlaid on top of the anatomical images. (Note that all analysis was performed on the resolution at which the data were acquired.)