Fig. 5
From: Cis-acting super-enhancer lncRNAs as biomarkers to early-stage breast cancer
Super-enhancers Identified in MCF10A progression series. a Super-enhancers quantified in the MCF10A progression series by H3K27ac signal applying the ROSE Algorithm. b Heatmap of super-enhancer regions classified in each cell line in MCF10A progression series and their H3K27ac signal in corresponding cell lines in the series (From Left to Right: MCF10A super-enhancers, AT1 super-enhancers, DCIS.com super-enhancers, and CA1 super-enhancers). Hierarchical Clustering was performed. c H3K27ac signal at AC080013.1 (RP11-379F4.4), the most promising potential cis-acting SE-lncRNA, and AL390719.2 (RP11-465B22.8), the highest up-regulated SE-lncRNA in progression. H3K27ac signal was normalized to mapped reads