Skip to main content

Table 2 Matrisome-encoding RNAs with differential expression in PAFs

From: A matrisome RNA signature from early-pregnancy mouse mammary fibroblasts predicts distant metastasis-free breast cancer survival in humans

Probe ID Gene symbol p-values (< 0.05) Fold change Preg/Ctrl Probe ID Gene Symbol p-values (< 0.05) Fold change Preg/Ctrl
UP     ILMN_1225835 Mfap5 0.0296 1.75
ILMN_2635784 Gpc1 0.0001 3.74 ILMN_2774315 Col13a1 0.0300 2.21
ILMN_1247540 Vcan 0.0003 3.1 ILMN_1256970 Adamts18 0.0323 1.71
ILMN_1246127 Prss23 0.0013 2.34 ILMN_2617087 Egln1 0.0347 1.84
ILMN_2463181 Tnc 0.0016 2.38 ILMN_1227502 Il15ra 0.0357 1.53
ILMN_2753809 Mmp3 0.0023 2.12 ILMN_1230599 Adam23 0.0362 1.78
ILMN_1243254 Adam12 0.0030 2.24 ILMN_3008858 Ctsc 0.0371 1.94
ILMN_2463180 Tnc 0.0036 2.4 ILMN_3158499 Mdk 0.0410 1.54
ILMN_2683958 Col3a1 0.0055 1.96 ILMN_2766028 Postn 0.0452 1.67
ILMN_2455596 Adamts18 0.0060 3.23 ILMN_2492264 Wisp1 0.0467 1.81
ILMN_2819929 Plod2 0.0064 1.57 ILMN_2688912 F10 0.0485 1.9
ILMN_1216882 Postn 0.0068 1.9 ILMN_2725927 Serpina3g 0.0488 1.88
ILMN_2769918 Timp1 0.0081 1.72 ILMN_2680415 Sema6d 0.0493 1.61
ILMN_1234487 Angpt2 0.0086 2.44 ILMN_2710698 Fgf21 0.0498 1.53
ILMN_1213850 Col4a3 0.0087 1.82 DOWN    
ILMN_3103896 Timp1 0.0091 1.78 ILMN_2486906 Wisp2 0.0001 − 3.31
ILMN_1221670 Col5a2 0.0092 2.29 ILMN_2686327 Gas6 0.0014 − 1.63
ILMN_2728729 Sdc4 0.0093 1.82 ILMN_2760019 Cxcl13 0.0015 − 2.7
ILMN_2735184 Col18a1 0.0116 2.71 ILMN_1231689 Sfrp1 0.0046 − 2.21
ILMN_2769884 Igf1 0.0119 1.43 ILMN_1229370 Podn 0.0094 − 2.85
ILMN_1253797 Slit2 0.0131 2.02 ILMN_1249485 S100g 0.0095 − 2.14
ILMN_2460257 Adam10 0.0154 1.7 ILMN_1219335 Igfbp3 0.0098 − 1.78
ILMN_2617090 Egln1 0.0166 1.84 ILMN_2851288 Ngfr 0.0121 − 1.73
ILMN_2731901 S100a4 0.0171 1.69 ILMN_1238597 Omd 0.0132 − 1.93
ILMN_2715840 C1qc 0.0172 1.79 ILMN_2595664 Dhh 0.0139 − 1.6
ILMN_1240458 Mfap2 0.0188 1.47 ILMN_2697220 Figf/Vegfd 0.0148 − 1.4
ILMN_2901626 Tnfref21 0.0212 1.95 ILMN_2773348 Bmp8a 0.0148 − 2.43
ILMN_2617086 Egln1 0.0224 1.69 ILMN_2461098 Plxnb2 0.0164 − 1.65
ILMN_2718204 Clec11a 0.0235 1.17 ILMN_2910653 Bmp8a 0.0183 − 2.35
ILMN_2671344 Adamts12 0.0242 1.65 ILMN_1251096 Spock2 0.0213 − 1.74
ILMN_1213777 Fgf10 0.0245 1.61 ILMN_2834379 Tgfbi 0.0252 − 1.73
ILMN_1260125 Fn1 0.0252 1.75 ILMN_1259632 Col20a1 0.0253 − 2.07
ILMN_2770429 Plod2 0.0252 1.73 ILMN_1252506 Fbn1 0.0261 − 2.63
ILMN_2638114 Ptn 0.0259 1.37 ILMN_2727503 Igfbp3 0.0297 − 2.63
ILMN_1239380 Leprel2 0.0280 1.71 ILMN_2507286 Tnfsf13b 0.0338 − 1.55
ILMN_2659151 Thbs1 0.0290 1.15 ILMN_2718401 Htra3 0.0392 − 1.82
ILMN_2486186 Tnfrsf1b 0.0291 1.75 ILMN_1234111 Vtn 0.0392 − 1.48
ILMN_1234413 Adamts12 0.0293 1.5 ILMN_1214439 Ltbp1 0.0426 − 1.51
  1. The table shows the 74 probes (Probe ID), representing 64 different RNAs, that encode proteins associated with the Matrisome [16] and are differentially expressed (p < 0.05) in fibroblasts from 3-days pregnant mouse mammary glands (Preg) compared to fibroblasts isolated from age-matched virgin control glands (Ctrl). Probes have been ranked by decreasing fold-change and increasing p-value