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Fig. 3 | Breast Cancer Research

Fig. 3

From: A matrisome RNA signature from early-pregnancy mouse mammary fibroblasts predicts distant metastasis-free breast cancer survival in humans

Fig. 3

(A) Immunohistochemical staining for VCAN and ALX4 (arrow heads) around outgrowing ductal epithelium in 3-days pregnant mouse mammary glands and in glands from age-matched adult virgin glands (representative images, n = 4 (VCAN) and 3 (ALX4) animals respectively; see also Additional file 6: Figure S4). Scale bars are 100 µm. (B) Confirmatory qRT-PCR results for selected RNAs (Gpc1, Wisp2, Alx4, and Vcan) in 3-days pregnancy-associated (P) and control fibroblasts (C). Bars represent standard errors (n = 3 animals). (C) Confirmatory qRT-PCR results for selected matrisome protein encoding RNAs Col3a1, Col18a1, and Tnc. Bars again represent standard errors (n = 3 animals)

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Breast Cancer Research

ISSN: 1465-542X

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