Fig. 4
From: Transcriptome analysis of heterogeneity in mouse model of metastatic breast cancer
Intratumoral heterogeneity observed across organ-derived cell lines. Bulk RNA analysis of the organ-derived cell lines revealed distinct expression patterns relevant to A cellular metabolism, B extracellular remodeling of the microenvironment, C stem cell signatures, and D cellular dormancy among the cell lines. Clusters were assigned based on CD44 expression and the metastatic origin of each cell line as shown in the lower right