SEARCH | Experienced incident CAD | Did not experience incident CAD | |
---|---|---|---|
N = 12,413 | N = 750 | N = 11,663 | |
Age at diagnosis | 54.6 (8.9) | 59.9 (7.1) | 54.2 (8.9) |
Received adjuvant chemotherapy | 4735 (38%) | 202 (27%) | 4533 (39%) |
Received adjuvant radiotherapy | 8773 (71%) | 535 (71%) | 8238 (71%) |
Received adjuvant hormonal therapy | 9496 (77%) | 580 (77%) | 8916 (76%) |
Histopathological grade | /10859 | /10207 | /652 |
Well Differentiated | 2088 (19%) | 132 (20%) | 1956 (19%) |
Moderately Differentiated | 5364 (49%) | 351 (54%) | 5013 (49%) |
Poorly/Undifferentiated | 3407 (31%) | 169 (26%) | 3238 (32%) |
Tumor maximum diameter (mm)* | 17 [11, 24] | 15.5 [10, 23] | 17 [11, 24] |
(Missing) | 2655 | 156 | 2499 |
Number of nodes excised* | 8 [4, 14] | 8 [4,13] | 8 [4, 14] |
(Missing) | 2934 | 170 | 2764 |
Number of nodes involved* | 0 [0, 1] | 0 [0, 1] | 0 [0, 1] |
(Missing) | 3219 | 198 | 3021 |
ER Status | /9150 | /548 | /8602 |
Negative | 1474 (16%) | 80 (15%) | 1394 (16%) |
Positive | 7676 (84%) | 468 (85%) | 7208 (84%) |
Highest level of education received | /11196 | /666 | /10530 |
Below GSCE | 2376 (21%) | 238 (36%) | 2138 (20%) |
GSCE or similar | 5721 (51%) | 322 (48%) | 5399 (51%) |
A-level or similar | 1493 (13%) | 54 (8.1%) | 1439 (14%) |
Graduate | 1606 (14%) | 52 (7.8%) | 1554 (15%) |
Index of Multiple Deprivation | 13.7 (9.4) | 15.1 (10.1) | 13.6 (9.3) |
Age at menarche | 12.8 (1.6) | 12.8 (1.7) | 12.8 (1.5) |
(Missing) | 1463 | 73 | 1390 |
Number of full-term pregnancies* | 2 [1, 2] | 2 [1, 3] | 2 [1, 2] |
(Missing) | 5 | 0 | 5 |
Height (cm) | 204 (167) | 190 (138) | 205 (168) |
Weight (kg) | 109 (171) | 107 (157) | 109 (172) |
BMI (kg/m2) | 26.8 (5.2) | 28.6 (5.6) | 26.7 (5.2) |
(Missing) | 830 | 39 | 791 |
Received hormonal replacement therapy | 4762/11888 (40%) | 381/728 (52%) | 4381/11160 (39%) |
Smoking history | /11815 | /719 | /11096 |
Never | 6363 (54%) | 305 (42%) | 6058 (55%) |
Past | 3534 (30%) | 262 (36%) | 3272 (29%) |
Current, in last year | 1918 (16%) | 152 (21%) | 1766 (16%) |
Alcohol Consumption | /12413 | /750 | /11663 |
Past | 4290 (35%) | 341 (45%) | 3949 (34%) |
Current | 8123 (65%) | 409 (55%) | 7714 (66%) |
Ethnicity | /11980 | /731 | /11249 |
European | 11,955 (~ 100%) | 730 (~ 100%) | 11,225 (~ 100%) |
African | 1 (< 0.1%) | 0 | 1 (< 0.1%) |
Asian | 2 (< 0.1%) | 1 (0.1%) | 1 (< 0.1%) |
Southeast Asian | 0 | 0 | 0 |
Other | 22 (0.2%) | 0 | 22 (0.2%) |
Thyroid disease | 1288/11874 (11%) | 115/724 (16%) | 1173/11150 (11%) |