Table 1 Participant characteristics according to 38-gene HGF signature expression, Carolina Breast Cancer Study, 1993–2013

Total

1329 (68%)

628 (32%)

Age^a

 < 40 years old

1522 (53%)

100 (47%)

21.25% (14.81, 27.68)

20.33% (14.05, 26.61)

 40–49 years old

498 (66%)

257 (34%)

8.25% (3.84, 12.66)

8.51% (4.29, 15.98)

 ≥ 50 years

679 (74%)

236 (26%)

Referent

Referent

Race^b

 Black

603 (58%)

430 (42%)

20.20% (16.19, 24.20)

19.93% (16.00, 23.87)

 Non-black

726 (79%)

198 (21%)

Referent

Referent

Grade^c

 III

337 (47%)

384 (53%)

43.94% (39.76, 48.13)

41.11% (36.68, 45.55)

 I/II

691 (91%)

71 (9%)

Referent

Referent

Stage^c

 Stage III/IV

208 (64%)

115 (36)

11.56% (5.39, 17.71)

6.16% (0.21, 12.11)

 Stage II

605 (63%)

349 (37%)

12.53% (8.06, 17.01)

7.89% (3.54, 12.22)

 Stage I

499 (76%)

158 (24%)

Referent

Referent

Postmenopausal BMI^c

 Obese

356 (73%)

132 (27%)

− 1.97 (− 9.10, 5.16),

− 6.23 (− 13.38, 0.92)

 Overweight

209 (73%)

76 (27%)

− 2.35 (− 10.20, 5.50)

− 3.71 (− 11.24, 3.83)

 Underweight/normal

159 (71%)

65 (29%)

Referent

Referent

Premenopausal BMI^c

 Obese

225 (56%)

176 (44%)

16.07 (8.95, 23.20)

5.70% (− 1.68, 13.09)

 Overweight

162 (65%)

86 (35%)

6.86 (− 1.02, 14.75)

2.62% (− 4.87, 10.11)

 Underweight/normal

205 (72%)

79 (28%)

Referent

Referent

Reproductive history^c

 Nulliparous

213 (71%)

85 (29%)

− 9.04% (− 15.07, − 3.02)

− 7.18% (− 12.91, − 1.46)

 Parous, breastfed

551 (73%)

203 (27%)

− 10.64% (− 15.11, − 6.18)

− 6.77% (− 11.09, − 2.45)

 Parous, never breastfed

565 (62%)

340 (38%)

Referent

Referent

Family history of breast cancer^c

 Yes

235 (68%)

110 (32%)

− 0.18% (− 5.62, 5.26)

1.14.% (− 3.96, 6.25)

 No

1053 (68%)

497 (32%)

Referent

Referent