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Fig. 5 | Breast Cancer Research

Fig. 5

From: Progesterone receptor antagonists reverse stem cell expansion and the paracrine effectors of progesterone action in the mouse mammary gland

Fig. 5

Regulatory motifs associated with RNA-binding proteins and RNA-binding proteins/splicing factors expressed in response to E + P. a RNA-binding protein motifs involved in alternative splicing were discovered using rMAPs. Differentially spliced genes (FDR < 0.1) in MaSC, LM, and LP lineages treated with EP relative to sham were examined for the motifs enriched in the alternatively spliced regions. RPKM values of the RNA-binding proteins were examined for correlation between EP-treated mice and the mice in control group in all the three cell lineages, b MaSC, c LP, and d LM. HNRNPA1 is indicated by the red triangle, HRNPA2B1 by the gold triangle

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