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Fig. 5 | Breast Cancer Research

Fig. 5

From: Single cell transcriptome atlas of mouse mammary epithelial cells across development

Fig. 5

Comparison of single cell transcriptomes of different strains. a t-SNE and ternary plots of the combined scRNA-seq transcriptomes of epithelial cells isolated from adult mammary glands (10 weeks) from three different mouse strains: FVB/N, C57BL/6, and SWISS (SW) (n = 3–4 pooled mice per strain), colored by strain. Mice were not staged for the estrus cycle. Mixed refers to mixed-lineage. b Same plots as a but colored by cell cluster. c Upper panels, same integrated t-SNE plot as in b but shown separately for each individual strain. Lower panels color cells by Mki67 expression instead of cluster. d Same t-SNE plot as a but colored by basal, LP and ML expression signatures. Red = high expression, gray = no expression. e Same t-SNE plot as a but colored by expression of lineage-specific marker genes

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