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Fig. 1 | Breast Cancer Research

Fig. 1

From: Analysis of genomic and non-genomic signaling of estrogen receptor in PDX models of breast cancer treated with a combination of the PI3K inhibitor alpelisib (BYL719) and fulvestrant

Fig. 1

ERα/Src and ERα/PI3K interactions in human tumoral breast samples. a ERα/Src (a, b) and ERα/PI3K (c, d) interactions were detected by proximity ligation assay (PLA) on two formalin-fixed paraffin-embedded breast tumor sections. The experiments were performed on two serial sections from the same tumor (Obj ×40). b Kaplan-Meier estimates of OS and DFS according to ERα/Src interaction. c Kaplan-Meier estimates of OS and DFS according to the ERα/PI3K interaction

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