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Table 2 Summary of the clinical MRI and SWE parameters for the 62 patients

From: Early assessment of shear wave elastography parameters foresees the response to neoadjuvant chemotherapy in patients with invasive breast cancer

Parameters

Responder (n = 34)

Non-responder (n = 28)

p value

MRI volume (mm3)

 VMRI1

104,589.2 ± 254,548.7 (24)

117,407.7 ± 164,022.0 (25)

0.17

 VMRI2

24,458.6 ± 65,700.82 (16)

115,921.4 ± 131,323.6 (7)

0.09

 VMRI3

16,939 ± 52,964.8 (14)

72,912.7 ± 123,127.2 (14)

0.04*

Mass size (mm)

 s1

27.1 ± 13.7 (28)

34 ± 20.5 (28)

0.27

 s2

16.5 ± 8.5 (32)

29.0 ± 16.5 (26)

< 0.001*

 s3

10.6 ± 6.6 (25)

24.3 ± 15.4 (24)

< 0.001*

Mean elasticity (kPa)

 Emean1

82.2 ± 38.0 (28)

92.1 ± 32.9 (28)

0.76

 Emean2

38.5 ± 22.7 (32)

60.0 ± 30.3 (26)

0.01*

 Emean3

29.5 ± 25.4 (25)

47.6 ± 33.3 (24)

0.03*

Maximum elasticity (kPa)

 Emax1

163.1 ± 55.7 (28)

179.6 ± 38.6 (28)

0.50

 Emax2

95.7 ± 51.1 (32)

134.9 ± 59.0 (26)

0.01*

 Emax3

63.4 ± 49.8 (25)

114.3 ± 72.9 (24)

0.02*

Ratio of mean elasticity

 Emean-ratio1

16.2 ± 14.8 (28)

26.0 ± 21.2 (28)

0.02*

 Emean-ratio2

10.9 ± 10.2 (32)

16.8 ± 14.9 (26)

0.07

 Emean-ratio3

5.3 ± 6.1 (25)

10.8 ± 9.8 (24)

0.02*

Ratio of maximum elasticity

 Emax-ratio1

16.6 ± 14.0 (28)

22.2 ± 14.0 (28)

0.08

 Emax-ratio2

14.3 ± 15.1 (32)

23.0 ± 31.8 (26)

0.22

 Emax-ratio3

6.1 ± 5.5 (25)

15.6 ± 16.2 (24)

0.02*

Mass characteristic frequency (Hz)

 fmass1

125.7 ± 71.2 (28)

119.1 ± 74.8 (28)

0.82

 fmass2

135.3 ± 72.2 (32)

105.0 ± 79.2 (26)

0.05

 fmass3

243.9 ± 156.3 (25)

102.2 ± 61.2 (24)

< 0.001*

Change of elasticity (kPa)

 Emean1–2

39.8 ± 35.9 (26)

31.3 ± 42.4 (26)

0.42

 Emean1–3

50.9 ± 41.4 (19)

45.6 ± 43.1 (24)

0.46

 Emax1–2

57.2 ± 60.8 (26)

48.5 ± 69.7 (26)

0.50

 Emax1–3

102.7 ± 56.0 (19)

65.8 ± 77.3 (24)

0.09

Change of mass characteristic frequency (Hz)

 fmass1–2

−8.9 ± 97.6 (26)

16.1 ± 86.3 (26)

0.90

 fmass1–3

−88.4 ± 98.4 (19)

16.1 ± 55.4 (24)

< 0.001*

  1. Data are mean ± standard deviation; data in parentheses are mass numbers
  2. Emean mean elasticity, Emax maximum elasticity, Emean_ratio ratio of the mean elasticity between the mass and the surrounding normal tissue, Emax_ratio ratio of the maximum elasticity between the mass and the surrounding normal tissue, fmass mass characteristic frequency
  3. The subscripts 1, 2, and 3 indicate the corresponding parameters measured at the first, the second, and the third visit, respectively
  4. *p < 0.05; the difference is statistically significant